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Leflunomide and teriflunomide: altering the metabolism of pyrimidines for the treatment of autoimmune diseases
Serious risks include pancreatitis, gallbladder disease, kidney issues, and possible gastroparesis or bowel obstruction, plus a boxed warning for thyroid Ccell tumors based on rodent data and a contraindication in patients with personal/family history of medullary thyroid carcinoma or MEN2
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