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Simultaneously, the signals of the top six common gastrointestinal AEs (nausea, diarrhea, vomiting, upper abdominal pain, constipation, and pancreatitis) for different GLP-1 RAs were detected and compared ( Table 3 )

Yuan Shen Justin Lim is now affiliated with Ipswich Hospital, East Suffolk and North Essex Foundation Trust, Ipswich, United Kingdom

Using pharmacy receipt data anchored to initial GLP-1 prescriptions in 2021 from a large PBM, one early study revealed that only 32% GLP-1 patients remained on these weekly injections after 12 months and only 15% after two years.[16] This is an 85% two-year rejection rate not too far off from otherwise successful, consumer packaged goods brands Ive worked with