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They are intended for adults with type 2 diabetes (or, for weight management, the approved brands Wegovy or Zepbound)
Tirzepatide is more effective for blood sugar control, and retatrutide was most effective in managing diabetic kidney disease and body weight
Del Buono MG, Montone RA, Camilli M, Carbone S, Narula J, Lavie CJ, Niccoli G, Crea F
The exception to this was K1 Cagri , the site of lipid conjugation, which adopts a different rotamer to K1 rAmy
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