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FOXO3 also upregulates the expression of dynamin-related protein 1 (DRP1), mitochondrial fission 1 protein (FIS1), and mitofusin 2 (MFN2) to regulate mitochondrial fission 100
this dipeptide is further hydrolysed by cell surface dipeptidases and the resulting amino acids taken up by cells for regeneration of intracellular GSH (Pompella et al., 2007)
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In this hypermetabolic state, the body releases a large number of reactive oxygen species (ROS), which can lead to thyroid epithelial cell damage, autoantigen activation of the immune system, and induction of autoimmune deterioration
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