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111 Erastin increases Fe 2+ levels and ROS production in breast cancer cells, promoting ferroptosis

Possible relevance of alpha lipoic acid contained in a health supplement in a case of insulin autoimmune syndrome

siRNA knockdown Macrophages (2.5 10 5 cells/mL) were seeded for 24 h and then were transfected with 10 nM of small interfering RNA (siRNA, GPx1 s804, s805, Thermo Fisher Scientific) or a negative control (Silencer Select siRNA Negative control 4394803, Thermo Fisher Scientific) following the manufacturers instructions

It activates AMPK , an energy-sensing pathway also affected by exercise and metformin