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2 In a key secondary endpoint, more than 65% of participants taking the highest dose of orforglipron achieved an A1C less than or equal to 6.5%, which is below the 3 In an additional key secondary endpoint, participants taking orforglipron lost an average of 16.0 lbs (7.9%) at the highest dose

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Shen Z created a CD44-targeted and ROS-responsive CS-BR-mediated multifunctional liposome loading celastrol (CS-BR@CLT) for the targeted therapy of AKI, which exhibited multiple anti-AKI functions [278]

Their anti-inflammatory and antioxidant properties further contribute to mitigating cardiac injury and improving overall cardiovascular health