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10.1007/s00109-016-1488-y 28 IlicS.BrcicI.MesterM.FilipovicM.SeverM.KlicekR.et al (2009)
side effects are generally mild [14]
IGF-IR interacts with NPM-ALK and then promotes T cell ALK + anaplastic large cell lymphoma cells survival [19]
While stimulation of IGF-1R by IGFs triggers autophosphorylation and subsequent phosphorylation of either insulin receptor substrate-1 (IRS-1) or insulin receptor substrate-2 (IRS-2), it is clear that these adapter proteins are activated by both IR 15 and IGF-1R
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