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The formation of gamma-glutamylcysteine is the rate-limiting reaction in GSH synthesis and is feedback inhibited by GSH itself, a mechanism responsible for the regulation of cellular GSH concentration
Clinicians should advise patients to maintain adequate fluid intake because decreased oral intake or increased loss of fluids can potentially lead to AKI
Its also important to stay active to support metabolism and muscle health
Psychopharmacology 199 , 583592 (2008)
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