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Negative side effects may include a paradoxical decrease in energy levels (most likely due to detoxification from methylation) or slight pain at the injection site which diminishes over 5-10 days
Key aspects of romiplostim administration include: Subcutaneous injection once weekly Initial dose based on body weight (1 mcg/kg) Dose adjustments according to platelet count Clinical Outcomes and Response Rates Studies show romiplostim greatly increases platelet counts in ITP patients
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