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However, decades later, many questions remain unanswered

When these receptors activate, they trigger the production of melanin, the pigment that gives skin and hair their color

It remains unclear whether A oligomers trigger ferroptosis by suppressing ferroportin and disrupting iron homeostasis, and how lipid peroxidation products generated during ferroptosis (such as 4-HNE) modify tau to accelerate its phosphorylation and aggregation