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"In addiction medicine, a lot of treatments target just one thing, for example, a nicotine patch helps with smoking, but not alcohol, but there is no medication that works across addictive substances, let alone all of them," said senior author Ziyad Al-Aly, MD, a WashU Medicine clinical epidemiologist and Chief of the Research and Development Service at the VA Saint Louis Health Care System

He is currently on no medications, however, he is allergic to sulfa drugs

MOTS-c operates through at least three converging pathways, each of which has distinct implications for its clinical applications

Alcohol Use Disorders Identification Test total, alcohol consumption, and alcohol problems scores were also assessed