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Data on treatment de-escalation, switching and discontinuation in older people with MS are a major unmet need, and dedicated studies should be designed to assess these strategies by use of non-inferiority frameworks and patient-preference trials, particularly in the context of real-world practice
The gastrointestinal side effects commonly associated with tirzepatideparticularly nausea, vomiting, and diarrhoeacan lead to reduced fluid intake and increased fluid losses
Finally, Ozempics favorable safety profile further reinforces our choice to integrate it into our medical weight-loss program
But the GLP-1s are not the benign, nearly invisible, drugs that flozins are
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