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Supporting this, data from our functional enrichment analysis of the transcriptome revealed notable upregulation of oxidative phosphorylation and the oxidative damage response in hepsin / mice treated with saline (data not shown)
Eighty percent agreed that further studies are needed (Figure 9)
At the top studied dose of 4.5 mg , cagrilintide produced a mean weight reduction of roughly 10.8% at 26 weeks , versus about 3.0% with placebo
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