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In DIO animals, long-term daily administration of this combination therapy, specifically in a stepwise manner, results in reduced energy intake and greater body weight loss over time when compared to chronic mono- and combined-treated groups, without affecting GLP-1 receptor, preproglucagon or amylin-receptor gene expression in the DVC
Like a lot of early adopters, I was after the minimum effective dose , enough appetite reduction to stay on track without killing my relationship with food
Try to eat foods that can help with nausea, such as ginger