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Nonetheless, many clinical investigations are limited by short follow-up durations, small sample sizes, heterogeneous formulations, and reliance on surrogate endpoints, such as variations in bacterial diversity or inflammatory markers, rather than definitive clinical outcomes, thereby limiting the robustness of current conclusions (2, 4)

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In contrast, GHK-Cu administered subcutaneously is released into the bloodstream instantly and in a controlled dose, which triggers more than 300 repair-related genes, helps to multiply fibroblast growth and contributes to the longevity of epidermal stem cells located in the basal layer

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