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17 This scale evaluates studies based on the selection of the study groups, comparability of the groups, and ascertainment of the outcome/exposure

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A common starting dose might be 0.25 mg once a week, and then it could go up to 0.5 mg, 1 mg, or even higher per week

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These recommendations are very consistent with the key points from the most current international guidelines, especially those published, in 2024 and 2025, by multi-society groups in both the US and the UK 1-3

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