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329,330 Compared with ACEIs and ARBs, targeting AGT theoretically offers a more comprehensive blockade of the RAAS, minimizing escape mechanisms while maintaining renal homeostasis and intact tubuloglomerular feedback, thereby enhancing both efficacy and safety
GLP-1 medications such as semaglutide work by influencing appetite signaling and slowing gastric emptying
Semaglutide a GLP-1-only agonist, used as the single-receptor reference arm in comparative incretin studies
Zepbound is a glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide 1 (GLP-1) dual receptor agonist
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