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129 Stabilized -catenin translocates to the nucleus and partners with TCF/LEF transcription factors to activate oncogenic targets, including MYC, Cyclin D1, LGR5, CD44, and ABCB1, genes that regulate proliferation, drug efflux, and stemness
[7] [8] References [edit] 1 2 3 GRCh38: Ensembl release 89: ENSG00000243955 Ensembl, May 2017 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000057933 Ensembl, May 2017 "Human PubMed Reference:"
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