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Avoid doing the shot too late in the afternoon or evening, as the extra energy you get, may lead to disruptive sleep patterns
First thing in the morning or before going to the gym is a good time
1999;44(8 Suppl):51S-56S
Depending on stimuli, microglia can adopt distinct phenotypes: the M1 pro-inflammatory state (induced by lipopolysaccharide and characterized by production of cytokines such as TNF-, IL-1, and IL-6) and the M2 anti-inflammatory state (induced by IL-4 or IL-13, promoting repair) [122, 123]
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