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[8] Early small-scale research suggested it may stimulate lipolysis (the breakdown of fat) and inhibit lipogenesis (fat storage), with preliminary data indicating it may not significantly affect blood glucose or insulin-like growth factor-1 (IGF-1) levels
In vitro enzyme-inhibition characterization
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12 Combinatorial approaches involving DDR inhibitors, epigenetic modulators, metabolic disruptors and immunotherapeutics hold promise for overcoming resistance and achieving durable clinical responses across malignancies
