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In 2013, Koeth et al
Treatment should be continued only if there is a beneficial metabolic response, typically defined as a reduction in HbA1c of at least 11 mmol/mol and weight loss of at least 3% at six months
If you place the unopened vial in a standard refrigerator (around 2C to 8C or 36F to 46F), it can remain stable for many months, often up to a year or more
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