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Keywords: melanin index, melanogenesis, oxidized glutathione, reduced glutathione, skin whitening, topical Introduction Skin aging is a complex biological phenomenon consisting of two independent clinically and biologically distinct processes, namely intrinsic aging and extrinsic aging. 1,2 Extrinsic aging (including photoaging) is the result of exposure to outdoor elements, primarily ultraviolet (UV) irradiation

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doi: 10.1183/09031936.00019307 94 MehtaAKSinghBPAroraNGaurSN