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Overall, no major changes of mean concentrations of blood NAD or glutathione metabolites occurred during aging, but subgroups who had lowered levels existed in all ages
These findings establish a critical role for GSH in promoting Rickettsia cell division and pathogenesis, contributing to the concept that GSH plays multifaceted roles in the fitness of intracellular pathogens
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Upon binding to estrogen, ER translocates to the nucleus where it binds to DNA regions containing estrogen-responsive elements (ERE) and subsequently regulates the transcription of numerous genes that are crucial for breast tumorigenesis [4]
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