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The mechanism involves the suppression of pro-inflammatory chemokine (C-C motif) ligand 20 (CCL20), which is of significant importance in the Th17 immune response, as well as IL-33, which is a key cytokine associated with Th2 immune responses [224]

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The agency has asked Novo Nordisk to list NAION as a side effect with a frequency of very rare in the product information that comes with the drugs

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Philadelphia: Saunders Elsevier

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