Six publications mentioned GSH as part of reviews related to melanin (kojic acid in rats, [15] piceatannol inhibition of mushroom tyrosin-ase, [16] oral zinc sulphate murine hair hypopigmentation, [17] hydro-quinone occupational exposure [18] (and toxicity for skin lightening) [19] and natural ingredient-containing treatments for hyperpigmen-tation
Exciting times, but careful evaluation of long-term safety, real-world outcomes, and patient access will be key From a neurological perspective, this overview is helpful, but what may become even more important is understanding how hormonal status shapes metabolic response
Common side effects include eye pain, blurred vision, conjunctival hemorrhage, and increased intraocular pressure, which are generally mild and temporary
These are not supplements to be purchased online and self-administered they are compounds that, when legally and clinically appropriate, require physician oversight, pharmaceutical-grade sourcing, and ongoing monitoring