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The specific gene expression alterations have been associated with axonal myelination and altered psychomotor development in DS individuals (Ponroy Bally and Murai 2021
GHK-Cu also modulates superoxide dismutase (SOD), the antioxidant enzyme that shields follicle stem cells from oxidative damage
308,309 EMT, CSCs, and DTPs are interconnected via regulatory networks involving transcription factors (e.g., SNAIL, ZEB1), 318 signaling cascades (e.g., TGF-), and cues from the TME (e.g., CAFs, hypoxia), collectively sustaining tumor heterogeneity and adaptive resistance
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