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[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing
Network medicine-based analysis of the Hepatoprotective effects of Amomum villosum Lour
7,8 Tumor heterogeneity, both spatial and temporal, adds another layer of complexity, as subclonal populations with distinct genetic and epigenetic features coexist and evolve under selective therapeutic pressure
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