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In the SURMOUNT-2 trial, which enrolled participants with type 2 diabetes, weight loss was somewhat lower but still substantial
Alternative pharmacological options with established safety profiles include: Semaglutide (Wegovy): Another GLP-1 receptor agonist with robust weight loss data and cardiovascular risk factor improvements (with cardiovascular outcome benefits demonstrated in the SELECT trial) Liraglutide (Saxenda): Daily GLP-1 agonist injection licensed for weight management Orlistat: Lipase inhibitor that reduces dietary fat absorption, available over-the-counter or on prescription Each has distinct side effect profiles and may suit different patient populations
This makes it appealing for patients who: Cannot tolerate systemic GH stimulation Need targeted fat metabolism support Are stacking with other metabolic therapies MOTS-c This mitochondrial-derived peptide is one of the most exciting developments in longevity medicine
For Women: Peptide therapy can ease the transition through perimenopause and menopause , improving mood, sleep, and metabolism while supporting skin texture, weight loss, and libido
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