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Provide lifestyle/diet/exercise support: semaglutide is an adjunct to behavior change, not a substitute
First, it provides anti-inflammatory support that can help manage the systemic inflammation associated with obesity and rapid metabolic change
Hepatic Effects: Instruct patients to promptly stop taking alogliptin and pioglitazone tablets and seek immediate medical advice if they experience signs or symptoms of liver injury (e.g., unexplained nausea, vomiting, abdominal pain, fatigue, anorexia or dark urine) [see Warnings and Precautions (5.4)]
They're given as a once-weekly injection under the skin, alongside a reduced-calorie eating plan and more physical activity
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