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Structure and function of the type 1 insulin-like growth factor receptor
Noom is basing its offering on a quarter dose of semaglutide 0.6mg per injection versus 2.4mg for Wegovy and said the rationale for the dose reduction comes from data gleaned from its members, as well as a couple of investigator-led studies published in The Lancet and New England Journal of Medicine
Breastfeeding individuals should also avoid GLP-1 medications, as it remains unknown whether these peptides transfer into breast milk or how they might affect nursing infants
But the mechanistic rationale is strong, the safety profile appears favorable, and the early observational data aligns with what the biochemistry predicts
