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The only meaningful comparison context is against the other agents in the class, covered in our Retatrutide vs Semaglutide vs Tirzepatide analysis, and the two entry points for the protocol itself are the 5 mg vial protocol for a gentle start and the Retatrutide 30mg dosage chart in units for higher maintenance targets

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In women with gestational diabetes, ~200 mg decreased insulin sensitivity by 18% and increased blood sugar by 19%.[68][70] Caffeine also raises cortisol ~50% above baseline, directly raising blood sugar.[71] Iron depletion: One cup of coffee with a meal reduces non-heme iron absorption by 39%

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