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The half-life of kisspeptin-54 is approximately 28 minutes, which is the primary challenge for therapeutic development
The second major comparative trial recently landed in Gastroenterology TEM or ESD in Early Rectal Tumors: A Clinical & Cost-Effectiveness Analysis The MUCEM Study (Beyer-Berjot et al., Gastroenterology 2026) The largest comparison of TEM/TAMIS and ESD to date: 330 patients across 23 French expert centers, prospective multicenter design
CLA: what it does and why it might matter CLA is a group of linoleic acid isomers found in meat and dairy from ruminant animals
Cagrilintide is engineered around that problem: it is a modified, lipidated peptide that acts as a dual amylin and calcitonin receptor agonist and is stable enough for once-weekly subcutaneous dosing
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