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These markers are useful when symptoms or risk factors suggest a functional deficiency that a high total B12 could be masking
As patients reduce food intake and sometimes forget to maintain fluid consumption, their overall hydration status declines
And so for me, eventually, when GLP-1s came out, it was like, No way, no how
That includes the anti-inflammatory effect, the ability to reduce cell death and promote autophagy, and also its indirect effects through blood pressure, obesity, and glucose/lipid metabolism
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