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Low glutathione levels have been linked to increased susceptibility to illnesses, including viral infections

For patients with hypotensive POTS (dysautonomia characterized by chronically low blood pressure), the nitric oxide-boosting, vasodilatory effects of Pycnogenol could theoretically lower blood pressure further, potentially exacerbating dizziness or fainting

Lifelong treatment with antioxidants has been recommended in an attempt to prevent morbidity and mortality associated with the disorder

Severe vitamin B12 deficiency can cause serious health problems, such as anaemia, nerve damage, and neurological problems