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Fluorescence intensities were measured at excitation/emission wavelengths of 488 nm/525 nm using a Leica TCS SP5 confocal microscope
In order to investigate the intracellular molecular transformation and the morphology transformation of NSBSO which showed good GSH-response in vitro and excellent selective cellular toxicity, we conducted LCMS, confocal laser scanning microscopy (CLSM) and Bio-TEM analysis
While collagen provides the structural framework, glutathione protects that framework from being broken down by environmental stressors
This approach could potentially benefit neurological conditions associated with oxidative stress and glutathione depletion, leveraging the compound's ability to cross the blood-brain barrier
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