During times of transition to hemodialysis or peritoneal dialysis, consideration must be given to insulin dosing adjustments for subjects with T1DM in efforts to maintain glycemic control
Al Qassab M, Mneimneh M, Jradi A, Derbas B, Dabboussi D, Khoury Baini J, et al
Interestingly, the same study found that, in rats, tirzepatide suppressed lipid intake without affecting sucrose (carbohydrate) consumption in a choice-based assay, implying that the effects of these medications may be macronutrient specific (Geisler et al., 2023)
However, semaglutide (2.4 mg weekly) is said to have broken the sound barrier (19), inducing 9.6% weight loss in patients with obesity and T2D (20) and 14.9% weight loss in patients with obesity alone (21) over 68 weeks of treatment