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The following dosage recommendations apply, unless otherwise prescribed: At the beginning of treatment, 1 vial of VITAMIN B12 DEPOT-ROTEXMEDICA (equivalent to 1000 g hydroxocobalamin acetate) is administered twice a week for the first few weeks after diagnosis

The same letter makes clear the peptides do not automatically move into Category 1 the bucket where the FDA has said it generally would not take action against compounders and that the Pharmacy Compounding Advisory Committee (PCAC) will review them at the July 2324, 2026 meeting, with February 2027 as the alternate date

Retatrutide is developed by Eli Lilly, the company behind tirzepatide (Mounjaro/Zepbound)

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