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3 If you take the pill, the FSRH advises adding a barrier method (such as condoms) for four weeks after starting Mounjaro and for four weeks after each dose increase, or switching to a non-oral method like the implant, IUD, patch, or ring
PlexusDx's oral tirzepatide option (at $349/mo month-to-month, or from $279/mo on the 6-month plan) works well for patients without baseline IBS or those who prefer daily pill therapy
The broader receptor activity of tirzepatide may contribute to slightly higher rates of early gastrointestinal intolerance, although discontinuation rates remain comparable 7
Amgen is developing a GLP-1/GIP dual agonist called MariTide (currently in phase 3 trials expected to complete in 2027), which is administered as a once-monthly injection
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