NAD+ 101, why Metabolism and Recovery Matter for Body Goals How NAD Supports Energy, Training, and Healing NAD+ functions as a cellular cofactor that supports mitochondrial efficiency, metabolic flexibility, and recovery from physical stress
Newer weight loss medications, particularly GLP-1 medications such as Ozempic, Wegovy, Mounjaro, and Zepbound, have been shown to significantly reduce body weight
Rework by Jason Fried & David Heinemeier Hansson Why Read It
In the Phase 2 obesity trial it produced about 24% weight loss at 12 mg over 48 weeks, the most of any drug in the class, and it cut liver fat by 86% in the people who started with fatty liver. In the 80-week Phase 3 obesity trial of 2,300 adults with an average BMI of 40, 12 mg produced 28% weight loss and 9 mg reached 26%