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Common GLP-1 Side Effects According to clinical literature and FDA labeling for approved GLP-1 medications, commonly reported side effects include nausea (especially when starting or after dose increases), vomiting, diarrhea, constipation, abdominal discomfort, decreased appetite, fatigue, and injection site reactions (for injectables)

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Important: These ranges apply only to liposomal glutathione, not to standard oral tablets

In this review, well review current understanding of these GPCRs physiological roles and mechanistic involvements in OA, and discuss emerging therapeutic targets that show promise in preclinical models of OA and/or in clinical trials