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Borlaug BA, Olson TP, Lam CS, Flood KS, Lerman A, Johnson BD, Redfield MM
Two residues with shorter side chains (I7 P and A13 P ) in GIP further weakened its binding to GLP-1R, consistent with the distinct cross-reactivity features of GIP and GCG with GLP-1R 5,6
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The phase 2 study followed adults with obesity for 48 weeks
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