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Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat

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Structure of 3G10-bound PV1 sVLP To elucidate the molecular basis of 3G10s specific recognition of PV1 sVLP but not wtVLP, we determined the cryo-EM structure of the sVLP in complex with the 3G10 Fab fragment at a nominal resolution of 2.60 (Fig