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This cycling approach prevents pituitary desensitization, where the gland becomes less responsive to repeated stimulation
compared to one: OR 1.86
The available data remain largely preclinical or based on limited observations, and its non-selectivity is also its main limitation: by affecting multiple receptors, it is associated with varied effects reported in the literature
Pharmacology of GLP-1 RAs Endogenous GLP-1 is secreted from intestinal L-cells following oral nutrient intake
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