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Arch Dermatol 146:234239 Osborne JE, Hutchinson PE (2002) A follow-up study to investigate the efficacy of initial treatment of lentigo maligna with surgical excision
Human trial doses often range from 1 to 3 grams per day and show modest benefits for fat mass and performance in some groups
Provider visits for evaluation, prescribing, and follow-up are in addition to the $50 medication copay and are billed through Medicare
The primary clinical concerns involve gastrointestinal (GI) side effects leading to dehydration, delayed gastric emptying affecting oral medication absorption, and increased aspiration risk during sedated procedures
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