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When patients can afford their medication without financial stress, they're significantly more likely to stay compliant, manage appointments, and follow through with the dietary and lifestyle support that amplifies semaglutide's effects

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Women using oral contraceptives should use an additional non-oral contraceptive method for 4 weeks after initiating tirzepatide and for 4 weeks after each dose increase

But sustained activation, the kind tirzepatide provides week after week, appears to allow the brain to adapt and may ultimately shift mood regulation in a positive direction