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Oral berberine at 1,000 to 1,500 mg daily has published human trial data

The preservation of muscle architecture and age-independent regenerative capacity through localized mIgf-1 transgene expression suggests clinical strategies for the treatment of age or disease-related muscle frailty

Foods to Prioritise and Foods to Limit Lean proteins, non-starchy vegetables, wholegrains, and healthy fats should be prioritised, whilst high-fat, fried, sugary, and spicy foods should be limited to reduce nausea and gastrointestinal discomfort