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Research indicates that during conventional weight loss, 65-80% comes from fat tissue and 20-35% from lean tissue, including muscle
doi: 0.1163/156856208784909435
Therefore, a thorough medical history may be helpful for differential diagnosis, but the differentiation of physiological oral mucosal melanin hyperpigmentation from single or multiple melanotic macules based on medical history and on clinical and histological grounds may be impossible as they share the same clinical and microscopical features and both may develop at a young age
Levy urged people interested in the practice to talk with their doctor or an obesity medicine specialist
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