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Bauer 2015): where In the first reaction (15), heme protein is oxidized by a molecule of hydrogen peroxide (H 2 O 2 ), resulting in the formation of Compound I , an oxoferryl (Fe IV = O) porphyrin cation radical, CAT[Fe IV = O(porphyrin + )]
Finally, since this was a noninferiority trial, we view the reported better mortality outcomes as interesting but unproven
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