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Free phenolic extract of BP expresses great effectiveness by increasing the reducing power that indirectly contributes to the reduced synthesis of melanin, which shows the usefulness of BP by protecting the cell from abnormal production of melanin (76, 135)

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Hence, there has been an increasing trend of recent studies investigating the sequenced or combined application of GSH with different bioactive(s), which can be categorized into three main types: plant metabolites (primary & secondary) and biostimulants