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Treatments with a family of lipid-lowering drugs known as fibrates (e.g., fenofibrate, bezofibrate) have been associated with an increased excretion of betaine in the urine and a rise in homocysteine concentration in the blood of patients with diabetes mellitus or metabolic syndrome (125, 126)
Low glutathione S-transferase P1 levels are associated with higher mortality in COVID-19 patients, and high levels of glutathione S-transferase P1 possibly offer protection for cellular redox reactions in severe COVID-19 infection, preventing deterioration especially in patients with co-morbidities like diabetes (Kumar D.S
The most enriched gene sets induced by GLP-1GIPLani corresponded to cell cycling and cholesterol metabolism (Extended Data Fig
BaardmanJVerberkSGSvan der VeldenSGijbelsMJJvan RoomenCSluimerJCet al
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